It really depends on what u like to do.
As far as clubs if u like to dance and drink Iguana Cantina, if u REALLY like to dance The Dox, if ur on more of a grown man tip then Red Maple, Club One, theres a new Club called Palma.
As far as shopping if ur not scared of the hood go to Mondawmin Mall, security has a few stores also. Shop Gentei, a new boutique called Chaos.
U can go to the inner harbor, ESPN Zone, Aquarium. All kinds of places to eat downtown and thru the city.
Like i said it all really depends on what u like to do.