Love that new splash intro. The dark interface is nice. I usually just use it to make GIFs and noticed the Animation window was gone. They changed it and made it into Timeline which is freakin' awesome. Now I don't have to open the movie files through File>Open As>Quicktime movie. Also playback of movie files on CS6 is much smoother and doesn't require Quicktime anymore.
Other than that, I haven't messed with other shit on there yet. So far so good.