Ultram
Generic Name: tramadol (TRAM a dol)
Brand names: Rybix ODT, Ryzolt, Ultram, Ultram ER
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What is Ultram?
Ultram (tramadol) is a narcotic-like pain reliever
Ultram is used to treat moderate to severe pain Ultram extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock
Ultram may also be used for other purposes not listed in this medication guide
Important information about Ultram
You should not take Ultram if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide Do not take Ultram while you are intoxicated (drunk) or taking any of the following: alcohol or street drugs, narcotic pain medicine, sedatives or tranquilizers, or medicine for depression, anxiety, or mental illness
Seizures (convulsions) have occurred in some people taking this medication Ultram may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting
Seek emergency medical attention if you think you have used too much of this medicine An Ultram overdose can be fatal
Ultram may be habit-forming Tell your doctor if you feel the medicine is not working as well in relieving your pain Never share Ultram with another person, especially someone with a history of drug abuse or addiction Keep the medication in a place where others cannot get to it
Do not crush an Ultram tablet Ultram is for oral (by mouth) use only Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death
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Before taking Ultram
You should not take Ultram if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide
Do not take Ultram while you are intoxicated (drunk) or taking any of the following:
alcohol or street drugs;
narcotic pain medicine;
sedatives or tranquilizers (such as Valium);
medicine for depression or anxiety; or
medicine for mental illness (such as bipolar disorder, schizophrenia)
Seizures have occurred in some people taking Ultram Talk with your doctor about your seizure risk, which may be higher if you have:
a history of drug or alcohol addiction;
a history of epilepsy or other seizure disorder;
a history of head injury;
a metabolic disorder; or
if you are also taking an antidepressant, muscle relaxer, narcotic, antipsychotic, or medicine for nausea and vomiting
To make sure you can safely take Ultram, tell your doctor if you have any of these other conditions:
kidney disease (or if you are on dialysis);
cirrhosis or other liver disease;
a stomach disorder; or
a history of depression, mental illness, or thoughts of suicide
FDA pregnancy category C It is not known whether Ultram will harm an unborn baby Ultram may cause serious or fatal side effects in a newborn if the mother uses this medication during pregnancy or labor Tell your doctor if you are pregnant or plan to become pregnant while using Ultram Tramadol can pass into breast milk and may harm a nursing baby You should not breast-feed while you are taking Ultram Do not give this medication to anyone younger than 16 years old without the advice of a doctor
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How should I take Ultram?
Take Ultram exactly as prescribed Never take Ultram in larger amounts, or for longer than recommended by your doctor Follow the directions on your prescription label Tell your doctor if the medicine seems to stop working as well in relieving your pain
Ultram can be taken with or without food, but take it the same way each time
Do not crush, chew, or break an Ultram ER tablet Swallow the tablet whole Breaking the tablet may cause too much tramadol to be released at one time This medicine is for oral (by mouth) use only Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death
If you use the Ultram extended-release tablet, the tablet shell may pass into your stools (bowel movements) This is normal and does not mean that you are not receiving enough of the medicine
Ultram may be habit-forming Never share Ultram with another person, especially someone with a history of drug abuse or addiction Do not stop using Ultram suddenly, or you could have unpleasant withdrawal symptoms Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication
Store Ultram at room temperature away from moisture and heat Keep track of the amount of medicine used from each new bottle Ultram is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription
What happens if I miss a dose?
Take the missed dose as soon as you remember Skip the missed dose if it is almost time for your next scheduled dose Do not take extra medicine to make up the missed dose
What happens if I overdose?
Overdose symptoms may include extreme drowsiness, shallow breathing, muscle weakness, slow heartbeat, cold or clammy skin, fainting, or seizure
What should I avoid while taking Ultram?
Do not drink alcohol It may cause a dangerous decrease in your breathing when used together with tramadol Ultram may impair your thinking or reactions Be careful if you drive or do anything that requires you to be alert
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Ultram side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Ultram: hives; difficulty breathing; swelling of your face, lips, tongue, or throat Stop using Ultram and call your doctor at once if you have any of these serious side effects:
agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
seizure (convulsions);
a red, blistering, peeling skin rash; or
shallow breathing, weak pulse
Less serious Ultram side effects may include:
dizziness, spinning sensation;
constipation, upset stomach;
headache;
drowsiness; or
feeling nervous or anxious
This is not a complete list of side effects and others may occur Call your doctor for medical advice about side effects You may report side effects to FDA at 1-800-FDA-1088
What other drugs will affect Ultram?
You may be more likely to have a seizure (convulsions) if you take Ultram while you are using certain other medicines Do not take Ultram without telling your doctor if you also use any of the following medications:
an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
an antidepressant such as amitriptyline (Elavil, Vanatrip), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft)
Cold or allergy medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by Ultram Tell your doctor if you regularly use any of these medicines, or any other pain medication
Tell your doctor about all other medicines you use, especially:
carbamazepine (Tegretol);
lithium (Eskalith, LithoBid);
ADHD medications (Adderall, Ritalin, Strattera);
an antibiotic such as clarithromycin (Biaxin), erythromycin (E E S , EryPed, Ery-Tab, Erythrocin), linezolid (Zyvox), rifampin (Rifadin, Rimactane, Rifater); or telithromycin (Ketek);
antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);
cancer medications such as gefitinib (Iressa), imatinib (Gleevec), or nilotinib (Tasigna);
a heart rhythm medication such as amiodarone (Cordarone, Pacerone), flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quin-G);
heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;
HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir, Kaletra); or
migraine headache medicine such as sumatriptan (Imitrex, Treximet)
This list is not complete and there are many other drugs that can interact with Ultram Tell your doctor about all medications you use This includes prescription, over-the-counter, vitamin, and herbal products Do not start a new medication without telling your doctor Keep a list of all your medicines and show it to any healthcare provider who treats you
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